SCD Guidelines

Standard of Care Guidelines for Patients with SCD

These guidelines were produced by the University of California, San Francisco Sickle Cell Center of Excellence (UCSF SCCoE) with funding from Networking California for Sickle Cell Care and UCSF Benioff Children’s Hospitals. UCSF created these Standard of Care Guidelines using the most up to date evidence-based recommendations from multiple well renowned sources such as the American Society of Hematology, American Thoracic Society, British Society for Hematology, and others. The authors compiled, to the best of their knowledge, all available evidence and have incorporated practices that are also derived from their experiences.

The Standard of Care Guidelines for Patients with Sickle Cell Disease (2024) is reviewed regularly and updated by the sickle cell team at the UCSF SCCoE. The UCSF SCCoE encourages suggestions and recommendations to these guidelines that should be submitted to: Images and text from these guidelines can only be used with the written permission of the UCSF SCCoE.

The most updated version and more information are available at